Friday , 14 December 2018

Evaluation of Anti-Ulcer and Anti-Inflammatory Activities of Arial Parts of Flemingia Macrophylla

D. Sujana*, B. Kumar, D. Vijay Kumar, P. Mounika, T. Kranthi Kumar, Sk. Rasheeda Begum
Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, Andhra Pradesh, India

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A major revolution in clinical neuropharmacology and psychopharmacology was herald during the past years. The natural compounds have played a major role in neurological disorders. A number of herbal drugs traditionally employed in the Indian system of medicine Ayurveda.  Herbal medicines are being used by about 80% of the world population primarily in the developing countries for primary health care. They have stood the test of time for their safety, efficacy, cultural acceptability and lesser side effects. The chemical constituents present in them are a part of the physiological functions of living flora and hence they are believed to have better compatibility with the human body. Ancient literature also mentions herbal medicines for age-related diseases namely memory loss, osteoporosis, diabetic wounds, immune and liver disorders, etc. for which no modern medicine or only palliative therapy is available.  The main aim of this study is to estimate the antiulcer &anti inflammatory activity of aerial parts of the plant based on the study of cytoprotective activity of flavanoids from the aerialparts of Flemingia macrophylla. Estimation of the activities will be done by In vitro & in vivo methods. The revealed results of the preliminary phytochemical screening of the ethanolic extract of dried aerial parts of Flemingia macrophylla.  The ethanolic extract has given positive results for flavanoids, glycosides. The results of preliminary phytochemical screening of the ethanolic extract of Flemingia macrophylla (FME) revealed that presence of flavonoids, glycosides. From the above studies it has been concluded that Flemingia macrfophylla has both antiulcer & anti inflammatory activity. Further studies are carrying to find out the active ingredients which are responsible for both activites.
Key words:  Cytoprotective activity, Flemingia macrophylla, Antiulcer & anti inflammatory

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