Thursday , 16 July 2020

A New Expedient Protocol for the synthesis of 1,4-Benzodiazepine derivatives (Substitute of HAART)

Dr. Meenakshi Agrawal*
Department of Chemsitry, Teerthanker Mahaveer University, Moradabad, India

A B S T R A C T
Facile expedient protocol based on the versatility and reactivity of intermediate (3) has been developed for finding potential substitutes of highly active antiretroviral therapy [HAART] as well as several molecular probes (8-11) have been developed to produce positive impact in overcoming the problem arising due to the emergence of the multidrug resistant mutants of the virus.
Keywords: Isatoic Anhydride, HAART, Etravirine, 1, 4-benzodiazepine, pyrimidine derivatives

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