Megha P*a, D. Ramesha, T. Yunus Pashaa, B. Ramesha, Rashmi N. Gb, K. Byrappab, Namratha Keerthirajb, Dr. Chandra Nayak Sb aDepartment of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G Nagar-571448, Nagamangala Taluk, Mandya, Karnataka. bCo-ordinator Vijnan Bhavan Manasagangothri University of Mysore. ABSTRACT Coumarin is an aromatic organic chemical compound it is described as a benzene molecule with ... Read More »
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Synthesis and Antimicrobial Studies on New Substituted 1,3,4-Oxadiazole Derivatives
Jyothi N Rao*, Pooja and Royline Department of Postgraduate Studies and Research in Chemistry, St Aloysius College, Mangaluru, 575003, India. A B S T R A C T A mixture of hydrazide, substituted aromatic aldehyde and ceric ammonium nitrate in dichloromethane taken in a beaker. Structures of the compounds synthesized were confirmed by IR, 1HNMR and Mass spectroscopic analysis. The ... Read More »
Samarium triflet: Sm(OTf)3 a simple and efficient catalyst for the synthesis of 1,4-dihydropyridine (Hantzsch pyridines)
M. Venkanna, Dr. B. Sammaiah, K. Srinuvasulu, Prof. R. Madhusudhan Raju* Department of Chemistry, Osmania University, Hyderabad-07, Telangana A B S T R A C T 1,4-Dihydropyridine synthesis has been carried out using Samarium triflet, as a catalyst. This protocol is applicable to a variety of aldehydes with β-ketoester and ammonium acetate to afford the corresponding Hantzsch pyridines in excellent ... Read More »
Synthesis and Characterization of 1-Phenyl-3-[4-(2-p-Cl-phenylimino-4-substitutedimino-1, 3, 5-dithiazino) amino phenyl]-prop-2-ene-1-ones
Dipak T. Tayade1*, Sanghapal S. Padhen2 1Dept. of Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604, (MS), India 2Dept. of Chemistry, Rajarshee Shahu Science College, Chandur Rly Dist Amravati-444904, (MS), India. A B S T R A C T Recently in this laboratory series of 1-phenyl-3-[4-(2-p-Cl-phenylimino-4-substituted imino-1,3,5-dithiazino)-amino phenyl]-prop-2-ene-1-ones (VIIIea-ee) had been synthesized by the interaction of 1-phenyl-3-[4-(5-p-Cl-phenyl-2,4-dithiobiureto) phenyl]-Prop-2-ene-1-ones ... Read More »
Synthesis, Characterization, Biological Evaluation and Docking studies of 2-(benzyl sulfonyl)-5-(3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazole Derivatives
G. Govindu*, D. Rajesh, P. Raveendra Reddy, L.K. Ravindranath Department of chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P-India A B S T R A C T New novel derivatives of 2-((4- substituted benzyl)sulfonyl)-5-(3-(4-( substituted phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazoles (9a-l as per scheme-I)were prepared by condensation of 2-(4-hydrazinylpyrimidin-5-yl)-5-((4-substituted benzyl)sulfonyl)-1,3,4-oxadiazole (8a-f) with various 4-substituted benzoic acids. The synthon 8a-f were obtained by the refluxing of 2-(4-chloropyrimidin-5-yl)-5-((4-substituted ... Read More »
Separation of Kawain, Flavokawain and 1,7-Diphenyl-5-hydroxy-6-heptene-3-one from the Rhizomes of Alipinia mutica using SWE-CNCC purification column technique
Yousif Jumaa A. Alrahmana, Mohd Marsin Sanagia,b, Abdulrahman Alzandic Hasnah Mohd Siratd , Wan Aini Wan Ibrahimd and Hassan Y. Aboul-Eneinde aDepartment of Chemistry, Faculty of Science and arts, Albaha University The kingdom of Saudi arabia bIbnu Sina Institute for Fundamental Science Studies, Nanotechnology Research Alliance, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysiya. cDean of faculty of science and ... Read More »
Various Synthesis Methods of 1,3,4-Oxadiazolederivatives: A Review
M Somashekhar*, R B Kotnal Department of Pharmaceutical Chemistry, Bldea’s College of Pharmacy, Vijaypur-586101. A B S T R A C T Heterocyclic molecules such as Oxadiazoles have been synthesized and evaluated for medical and agricultural activities. The disubstituted Oxadiazoles have executed a range of pharmacologic activities. 1,3,4-oxadiazole and 1,2,4-oxadiazole are better known, and more widely studied by researchers Among ... Read More »
Synthesis, Characterisation and Biological Evaluation of Novel Di substituted Quinazoline Linked with Cis Substituted Thio morpholine and 1, 2, 4 Triazole Moieties
V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, Andhra Pradesh, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, Andhra Pradesh, India. A B S T R A C T A series of Quinazoline derivatives11 (a-f) were prepared by Nucleophilic substitution reaction of 2,4 di chloro ... Read More »
Synthesis Charecterization and biological evaluation of 1-(5-(4-aminobenzoyl) -2,2-dimethyl-1,3,4-Oxadiazole-3(2H)-yl)ethanone
V. Prabhakar1*, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2, V. Krishna Murthy Naik2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, A.P, India A B S T R A C T Synthesis of 1,3,4 oxadiazole derivatives containing aromatic rings were synthesised by the condensation of ... Read More »
A New Expedient Protocol for the synthesis of 1,4-Benzodiazepine derivatives (Substitute of HAART)
Dr. Meenakshi Agrawal* Department of Chemsitry, Teerthanker Mahaveer University, Moradabad, India A B S T R A C T Facile expedient protocol based on the versatility and reactivity of intermediate (3) has been developed for finding potential substitutes of highly active antiretroviral therapy [HAART] as well as several molecular probes (8-11) have been developed to produce positive impact in overcoming ... Read More »