Thursday , 13 May 2021

Tag Archives: GLP-1

Preclinical safety, toxicology and efficacy studies of Recombinant Exendin-4 (Antidaibetic peptide) on wistar rats

U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T Recombinant Exendin-4 is a 39 amino acid peptide which exhibits sequence identity over 30 amino acids with mammalian glucagon like peptide-1 (GLP-1) and shares many of the gluco-regulatory ... Read More »

Acute Toxicity Study of Recombinant Exendin-4 in Swiss Albino Mice

Gowthami Vangala*1, Sumasri Guntupalli2, Venugopalaiah Penabaka3, Pasupuleti Naresh3 1Department of Biotechnology, Virchow Biotech Private Limited, Hyderabad, Telangana, India 2Department of Pharmacology, Shri Vishnu College of Pharmacy, Andhra Pradesh, India 3Department of Pharmaceutics, Ratnam Institute of Pharmacy, SPSR Nellore, Andhra Pradesh, India A B S T R A C T Recombinant Exendin-4 is a 39 amino acid peptide which exhibits sequence ... Read More »

Acute Toxicity Study of Recombinant Exendin-4 in Swiss Albino Mice

Gowthami Vangala*1, Sumasri Guntupalli2, Venugopalaiah Penabaka3, Pasupuleti Naresh3 1Department of Biotechnology, Virchow Biotech Private Limited, Hyderabad, Telangana, India 2Department of Pharmacology, Shri Vishnu College of Pharmacy, Andhra Pradesh, India 3Department of Pharmaceutics, Ratnam Institute of Pharmacy, SPSR Nellore, Andhra Pradesh, India A B S T R A C T Recombinant Exendin-4 is a 39 amino acid peptide which exhibits sequence ... Read More »

Role of DPP IV Inhibitor in Type-2 Diabetes Mellitus

ABOUT AUTHOR Anup K. Chakraborty*, Umesh K. Patil Department of Pharmaceutical Chemistry, School of Pharmacy & Research Centre, People’s University, Bhanpur, Bhopal-462037(M.P), India. E-mail: anup.ckbty@yahoo.co.in ABSTRACT Incretin hormones are defined as intestinal hormones released in response to nutrient ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin effect is mainly caused by two peptide hormones, glucose-dependent insulin releasing ... Read More »

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