Sunday , 14 August 2022

Tag Archives: Apoptosis

Fluorescence resonance energy transfer (FRET) based high throughput drug screening for the determination of antineoplastic activity of natural compounds from herbs

Sharmistha Gupta1 and Mithun Mukherjee2 1West Bengal State Council of Science and Technology, West Bengal-India  2Ramakrishna Vivekananda Mission Institute of Advanced Studies, West Bengal-India ABSTRACT Objectives:  In the present experiment a very useful cell-based high throughput screening method that uses a novel bio-sensor which specifically identifies apoptosis based on fluorescence resonance energy transfer technology. Methodology: A stable HeLa cell line ... Read More »

Screening of Natural Plant Phenol Compounds as Better Interacting Agents in Cancer Chemotherapy

Srinivasulu Boya1, Srinivasulu Cheemanapalli1, Madhusudana Pulaganti1, Anuradha CM2, Chitta Suresh Kumar1*  Department of Biochemistry, BIF, Sri Krishnadevaraya University, Anantapuramu-515003. Department of Biotechnology, Sri Krishnadevaraya University, Anantapuramu-515003. Abstract Cell death is a normal facet of human physiology, ensuring tissue homeostasis by offsetting cell production with cell demise. Neoplasm arises in part because of defects in physiological cell death mechanisms, contributing to ... Read More »

Review on Activator and Inhibitors of Programmed Cell Death: Vital Role in Heart Diseases

ABOUT AUTHOR  Hema Arya*, Bharat Bhushan, Komal Gupta  Department of Pharmacy, Ram-Eesh Institute, Greater Noida, UP, India Abstract Apoptosis of cardiomyocytes is seen in acute myocardial infarction where it may contribute to infarct size, and also in chronic heart failure, where it may be responsible for the gradual decline in cardiac function. Apoptosis of vascular smooth muscle cells is both ... Read More »

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