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Synthesis and Biological Evaluation of Coumarin -3-Substituted-Oxadiazole Derivatives

Megha P*a, D. Ramesha, T. Yunus Pashaa, B. Ramesha, Rashmi N. Gb, K. Byrappab, Namratha Keerthirajb, Dr. Chandra Nayak Sb aDepartment of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G Nagar-571448, Nagamangala Taluk, Mandya, Karnataka. bCo-ordinator Vijnan Bhavan Manasagangothri University of Mysore. ABSTRACT Coumarin is an aromatic organic chemical compound it is described as a benzene molecule with ... Read More »

Second order derivative spectrophotometry for simultaneous determination of Hg(II) and Ti(IV) using 3,4-dihydroxybenzaldehyde isonicotinoylhydrazone (DHBINH)

Dr. Srinivas Jagarlapudi*, Dr. V. Suryanarayana Rao, A. Ravi Kumar, Panchumarthi Srinivas, CH. Sunil Babu Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana-500090, India. A B S T R A C T A second order derivative spectrophotometric method is developed for the simultaneous determination of mercury (II) and titanium (IV) using 3, ... Read More »

Synthesis and Antimicrobial Studies on New Substituted 1,3,4-Oxadiazole Derivatives

Jyothi N Rao*, Pooja and Royline Department of Postgraduate Studies and Research in Chemistry, St Aloysius College, Mangaluru, 575003, India. A B S T R A C T A mixture of hydrazide, substituted aromatic aldehyde and ceric ammonium nitrate in dichloromethane taken in a beaker. Structures of the compounds synthesized were confirmed by IR, 1HNMR and Mass spectroscopic analysis. The ... Read More »

Synthesis and Characterization of 1-Phenyl-3-[4-(2-p-Cl-phenylimino-4-substitutedimino-1, 3, 5-dithiazino) amino phenyl]-prop-2-ene-1-ones

Dipak T. Tayade1*, Sanghapal S. Padhen2 1Dept. of Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604, (MS), India 2Dept. of Chemistry, Rajarshee Shahu Science College, Chandur Rly Dist Amravati-444904, (MS), India. A B S T R A C T Recently in this laboratory series of 1-phenyl-3-[4-(2-p-Cl-phenylimino-4-substituted imino-1,3,5-dithiazino)-amino phenyl]-prop-2-ene-1-ones (VIIIea-ee) had been synthesized by the interaction of  1-phenyl-3-[4-(5-p-Cl-phenyl-2,4-dithiobiureto) phenyl]-Prop-2-ene-1-ones ... Read More »

Synthesis and Spectral Characterization of Some 1,3,5-Dithazines with Chalcone Backbone

Dipak T. Tayade*1, Siddharth A. Waghmare2 1Dept. of Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604, M.S, India 2Dept. of Chemistry, Ghulam樂威壯 Nabi Azad College, Barshitakli, Akola-444 404, MS, India. A B S T R A C T Recently, a series of (2E)-1-{4-[2-(prop-2-en-1-yl)-4-substitutedimino-1,3,5-dithiazino-6-yl]aminophenyl}-3-(3,4-dimethoxy phenyl) prop-2-en-1-one (IIIa-e) had been synthesized by refluxing (2E)-1-[4-(5-(2-methylpropan-2-yl)-2,4-dithiobiureto) phenyl]-3-(3,4-dimethoxy phenyl) prop-2-en-1-one (I) with alkyl/aryl ... Read More »

Synthesis, Characterisation and Biological Evaluation of Novel BIS 1,3,4-Thiadiazole ring containing Indole and pyridine Moieties

V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A P, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu – 515003 (A.P) India A B S T R A C T The article is aimed to synthesize, characterize and screening the biological activity of 2-(5-(1H-indole-2-yl)-1, 3, ... Read More »

Synthesis, Characterization, Biological Evaluation and Docking studies of 2-(benzyl sulfonyl)-5-(3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazole Derivatives

G. Govindu*, D. Rajesh, P. Raveendra Reddy, L.K. Ravindranath Department of chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P-India A B S T R A C T New novel derivatives of 2-((4- substituted benzyl)sulfonyl)-5-(3-(4-( substituted phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazoles  (9a-l as per scheme-I)were prepared by condensation of 2-(4-hydrazinylpyrimidin-5-yl)-5-((4-substituted benzyl)sulfonyl)-1,3,4-oxadiazole (8a-f) with various 4-substituted benzoic acids. The synthon 8a-f were obtained by the refluxing of 2-(4-chloropyrimidin-5-yl)-5-((4-substituted ... Read More »

Various Synthesis Methods of 1,3,4-Oxadiazolederivatives: A Review

M Somashekhar*, R B Kotnal Department of Pharmaceutical Chemistry, Bldea’s College of Pharmacy, Vijaypur-586101. A B S T R A C T Heterocyclic molecules such as Oxadiazoles have been synthesized and evaluated for medical and agricultural activities. The disubstituted Oxadiazoles have executed a range of pharmacologic activities. 1,3,4-oxadiazole and 1,2,4-oxadiazole are better known, and more widely studied by researchers Among ... Read More »

Synthesis Charecterization and biological evaluation of 1-(5-(4-aminobenzoyl) -2,2-dimethyl-1,3,4-Oxadiazole-3(2H)-yl)ethanone

 V. Prabhakar1*, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2, V. Krishna Murthy Naik2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, A.P, India A B S T R A C T Synthesis of 1,3,4 oxadiazole  derivatives containing aromatic rings were synthesised by the condensation of ... Read More »

Synthesis of s-Triazine substituted analogues of 1,5-benzodiazepines of medicinal interest

Vandana Singh*, Aditi Anand and D. Kishore  Department of Chemistry, Banasthali University, Banasthali-304022 (Rajasthan), India Abstract Synthesis of a series of 1,5-benzodiazepines substituted on its 3 and 4 positions with 2’-(amino /ethylamino/ piperidino-(4,6-biscyclopropylamino)) -1,3,5-triazines 12,10,7 and 14 respectively, from 2-methyl-1,5-benzodiazepin-4-one (4) has been described. Keywords: 1,5-Benzodiazepine, 2,4,6-trichloro-1,3,5-triazine.   Read More »

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