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About author : Amir Khan*, Sarita Kumari, Fouzia Ishaq Dept. of Biotechnology & Biochemistry Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences & Research, Dehradun, India *e-mail: amiramu@gmail.com INTRODUCTION : Chirata is dried aerial part of annual herb swertia chirata found in temperate Himalaya and belong to family Gentianaceae.It is also known as Indian gentian. Biological Name: Swertia chirata, Gentiana ... Read More »
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Synthesis and Reactivity of Some Novel Quinazoline Derivatives
About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: dhanipharmachem@gmail.com ABSTRACT Quinazoline is a bicyclic compound earlier known as benzo- 1, 3-diazine. The name quinazolinone (German: Chinazolin) was proposed for its compound by Weddige, on observing that this was isomeric with the then compound cinnoline and quinaoxaline. The numbering of the quinazoline ring system which is currently ... Read More »
Synthesis and characterization of 3-[(5-phenyl hydroxyl-1, 3, 4-oxadiazol-2-yl) methyl amino]-2-methyl quinazolin-4(3h)-one
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Quinazolinone is a heterocyclic compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, ... Read More »
Pharmacology and Toxicology of Amphetamine and Related Designer Drugs
Pharmacology and Toxicology of Amphetamine and Related Designer Drugs Khursheed Asghar Errol De Souza The abuse of amphetamines is of national concern from a public health perspective. Review of this subject is timely and important, because the problem of amphetamine-like drugs has recently been amplified by the introduction of designer drugs in the illicit market. There has been an increasing ... Read More »
Synthesis and characterization of 3-((5-phenyl-1, 3, 4-oxadiazol-2-yl)Methyl amino)-2-methyl quinazolin-4(3H)-one
About author : Ramesh Dhani JNTUA – OTRI, Anantapur, India Dept.of Pharmaceutical Chemistry E-mail: dhanipharmachem@gmail.com ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, ... Read More »
SYNTHESIS AND CHARACTERIZATION OF 3-[(5-(4-CHLOROPHENYL) 1, 3, 4-OXADIAZOL-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONE
About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS ... Read More »
BENZOXAZOLE: THE MOLECULE OF DIVERSE PHARMACOLOGICAL ACTIVITIES
About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Oxazole is a heterocyclic organic compound that has a five-member ring molecular structure, containing oxygen, nitrogen as heteroatoms at its 1, 3-positions. Benzoxazoles are derivatives of oxazoles. Benzoxazoles is a planar molecule with conjugated p electrons sextets in the cyclic systems. The lone pair of ... Read More »
