Thursday , 30 March 2023

Oxidative Stress and Inflammation

Kamalakararao Konuku1*, Krishna Chaitanya Karri1, Patricia Ponce-Noyola2, John Dogulas Palleti2, Venugopal Reddy Bovilla3, S.B.Padal4, RajyalakshmiAmancherla5, Anjali jha6, Dr. M. Muthulingam7, Govinda Rao Duddukuri1
1Department of Biochemistry, Institute of Science, GITAM University, Visakhapatnam, A.P, India.
2Department of Life Sciences, University of Guanajuato, Mexico.
3Department of Biochemistry, JSS Medical College, JSS University, Mysore.
4Department of Botany, Andhra University, Visakhapatnam, Andhra Pradesh, India.
5Director, Bio world research technologies, Hyderabad, Telangana, India.
6Department of Chemistry, Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, India.
7Assistant Professor of Zoology, Faculty of Science, Annamalai University, Tamilnadu, India

Oxidative stress is an imbalance between prooxidant and antioxidant system, it is associated with upregulation of reactive oxygen species and reactive nitrogen species, these reactive oxygen species causes radical induced inflammatory diseases and cancer. Many synthetic antioxidants are useful for curing radical induced inflammatory diseases, due to side effects of these drugs, ethanopharmacologists focus on development of plant derived antioxidants for formulation of safer and effective antioxidant drugs.
Keywords: Antioxidants, inflammation, reactive oxygen species, oxidative stress, superoxide dismutase, curcumin.

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