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About author :
Abhilash A*, Prabhu Raj KJ, Gopi Krishna B, Dr. Hindustan Abdul Ahad
B. Pharmacy, Balaji College of Pharmacy, Anantapur, AP, India
*e-mail: [email protected]
Abstract:
Microgels, or intramolecularly cross-linked macromolecules(ICMs), have been known for a number of years. These gelation theories did not predict that such microgels made in solution could be prepared from such polyfunctional reactive solutions at complete reaction and high concentrations, without gelation. Microgels have been successfully and usefully prepared, however, at complete conversion of their contained reactive groups by theuse of either aqueous or non-aqueous dispersion polymerization in which surfaceactive agents are utilized to contain the polymerization to isolated submicron-sizedomains. The progression towards macro gelation is constrained to the maximum sizeof the dispersed domains. This paper demonstrates the contrasting general observationthat macro gelation in solvents of such polyfunctional reactive precursors cannotoccur below a Critical Gelation Concentration (CGC) if a carefully selected matchof solvent solubility parameters for the polymerization solvent and the formed polymeris made. In additionpolymerization the molecular weight of the produced ICMs may be varied in a simplecontrollable manner from the low thousands (Nanogels) to many millions (microgels)simply by the choice of concentration at which they are prepared. The products are adistinct form of polymer which is quite different to the linear analogue and almostcertainly these solution-prepared products are different to the microgels formed byaqueous dispersion polymerization techniques. This new solution technique provides asimple and general new method for the ready synthesis and design of an enormousrange of bespoke globular polymers having both fundamental academic interest and potential commercial utility.
Key words: Macro molecules, Micro gels, globular polymers.
