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Synthesis of the new carboxylic α,α-diamino ester: Methyl 2-benzamido-2-(N-benzyl N-ethylamino) acetate

El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco A B S T R A C T A simple synthetic approach to racemic methyl 2-benzamido-2-(N-benzyl N-ethylamino) acetate in high yield is reported. This synthesis involves the N-alkylation reaction between methyl α-bromo glycinate or ... Read More »

Synthesis of the new carboxylic α,α-diamino ester: Methyl 2-benzamido-2-(N-benzyl N-methylamino)acetate

El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco  A B S T R A C T The title compound, Methyl 2-benzamido-2-(N-benzyl N-methylamino) acetate was synthesized in high yield by N-alkylation reaction between methyl α-bromo glycinate or methyl α-azido glycinate N-benzoylated and N-benzyl-N-methylamine ... Read More »

Formulation and Evaluation of Lamivudine Extentended Release Tablets

Dr. Srinivas Jagarlapudi, A. Ravi Kumar*, Panchumarthi Srinivas, M. Raveendra Babu, Alekhya Jagarlapudi Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana. India- 500090. A B S T R A C T Now a day’s, Novel drug delivery system that plays a major role in the delivery of drug to specific site for ... Read More »

Left Diabetic Foot Ulcers Due to Trauma Associated with Pad [Peripheral Arterial Disease]: Split Thickness Skin Grafting With Antibiotics

S. Parveen*1, S. Sunil kumar*2, B. Benjamin Samuel2, B. Mayuri, S. Gousea begam 1Assistant professor, Department of Pharmacology, Santhiram College of Pharmacy, Nandyal, Kurnool, Andhra Pradesh, India-518501. 2Pharm.D, Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal, Kurnool, Andhra Pradesh, India, Pincode-518501. A B S T R A C T Diabetic foot ulcers were mainly caused due to microbial infection. ... Read More »

Analytical Method development for the Estimation of Related Substances by High performance Liquid Chromatographyfor the Rimonabent (RIM) drug

Dr. K. Mukkanti1, Dr. Srinivas Jagarlapudi2, Panchumarthi Srinivas*1, A. Ravi Kumar2, P. Ramyasree2 1Research Supervisor of Centre for Environment Institute of Science and Technology (Autonomous) Jawaharlal Nehru Technological University, Hyderabad, Telangana. India-500085. 2Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana. India- 500090. A B S T R A C T The main aim ... Read More »

Analytical Method Development and Validation for Lamivudine and Zidovudine Combine Pharmaceutical Dosage Forms by RP-HPLC

Dr. Gampa Vijay Kumar*1, Dr. T. Rajesh2, C. Mounika3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2,3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.  A B S T R A C T A new method was established for simultaneous estimation of Lamivudine and Zidovudine by RP-HPLC method. ... Read More »

Second order derivative spectrophotometry for simultaneous determination of Hg(II) and Ti(IV) using 3,4-dihydroxybenzaldehyde isonicotinoylhydrazone (DHBINH)

Dr. Srinivas Jagarlapudi*, Dr. V. Suryanarayana Rao, A. Ravi Kumar, Panchumarthi Srinivas, CH. Sunil Babu Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana-500090, India. A B S T R A C T A second order derivative spectrophotometric method is developed for the simultaneous determination of mercury (II) and titanium (IV) using 3, ... Read More »

Analytical Method Development and Validation for the Estimation of Lacidipine in Bulk and Dosage Form by RP-HPLC

Dandu Girija1*, Akkimi Padma1, A. Thirupathireddy2, B. Venkateswara reddy3 1Assistant professor, Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh       pin -523370. 2Associate Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh  pin – 523370. 3Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta (M), ... Read More »

Evaluation of Wound Healing Activity of Ethanolic Extract of Areial Parts of Cardiospermum Helicacabum LinnIn Albino Rats

Dinesh.A*, Dr. Jayasankar Reddy G Department of Pharmacology, Krishna Teja Pharmacy College, Tirupati-517506, Andhra Pradesh, India. A B S T R A C T Cardiospermum halicacabum (Linn) popularly called as balloon wine belongs to Sapindaceae family. Phytochemical constituents such as flavones, apigenin, triterpenoidal glycosides fatty acids and volatile ester have been reported in C. halicacabum. In the present study the ... Read More »

A Spreadsheet Program for One Compartment IV Bolus Administration

Reshma Fathima.K*, Salini.C, Y. Haribabu Department of Pharmaceutics, Grace College of Pharmacy, Palakkad A B S T R A C T Pharmacokinetics softwares plays a crucial role in the pharmaceutical field. Improvements in the quantitative analysis of drugs in biological tissues, such as plasma, and the increasing sophistication of computers and softwares along with access to the internet have greatly ... Read More »

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