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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Formulation and In-vitro Evaluation of Methylphenidate Pulsatile Tablets Using Press Coating Technology

Dr. A. kishore babu1, Dr. M. Venkata Ramana2, T. Kalapraveen3 1Professor, AM Reddy Memorial College of Pharmacy, Narasaraopet. 2Professor, GBN Institute of Pharmacy, Edulabad, Rangareddy. 3Associate Professor, DCRM Pharmacy College, Inkollu. A B S T R A C T In the present research work pulsatile drug delivery system of Methylphenidate tablets were formulated by employing compression coating technology. Initially the ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ceftolozane and Tazobactam in Its Bulk and Pharmaceutical Dosage Forms

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, R. Mahesh Babu3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Dolutegravir and Rilpivirine in Its Pure and Pharmaceutical Dosage Form

Sonalika Patro1, Ramesh Dhani1*, V. Haribaskar1, K. Sivasankar2 1Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh 2Department of Chemical Engineering, SVU University, Tirupathi, Andhra Pradesh ABSTRACT A Simple Rapid, Precise and Accurate High Performance Liquid Chromatography method was Developed and Validated for Determination of Dolutegravir and Rilpivirine in Bulk and Pharmaceutical Dosage Form. The Method Development was ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Amitriptyline Hydrochloride and Pregabalin in Bulk and Pharmaceutical Dosage Form

K. Suma, Rameeja Pattan*, V. Hari Baskar, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore. ABSTRACT A simple, accurate ,precise method was developed for the simultaneous estimation of the amitriptyline hydrochloride and pregabalin  in tablet dosage form .chromatogram was run through ODS (250MM 4.6mm,5µ).Mobile phase containing potassium dihydrogen ortho phosphate as buffer and acetonitrile  in the ... Read More »

Synthesis, Characterization and Biological Activities of Thiadiazole Derivative

G. Nagaraju*1, Dr. Sunil Kumar bainda*2 1Research Scholar, Department of Pharmaceutical Chemistry, OPJS University, Churu, Rajasthan 2Dr. Sunil Kumar, OPJS University, churu, Rajasthan A B S T R A C T Isatin (indole-2, 3-dione) is an endogenous compound, widely distributed in mammalian tissues and body fluids. Isatin chemically known as 1H-indole-2, 3-Dione. It   is a unique molecule possessing both amide ... Read More »

Development and Validation of a New Method for the Simultaneous Estimation of Metformin and Linagliptin in Bulk and Dosage form by using UV–Spectrophotometry

M. Mallikarjuna*, C. Guru Sudhakar, K. Siva Shankar, SK. Abid, P. Rameeja Ratnam Institute of Pharmacy, Pidathapolur, Nellore, AP, India ABSTRACT A Simple, Determined, and precise method to develop a new quantitative simultaneous identification of metformin hydrochloride and Linagliptin in combined pharmaceutical dosage forms. This method was based on the based on the UV spectrophotometric method for the simultaneous estimation of ... Read More »

Simultaneous Estimation of UV Spectroscopy and Method Development and Validation for Lansoprazole and Domperidone by RP-HPLC

Sanju Srinivas1, Marium Nazneen2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T A new method was established for simultaneous estimation of Lansoprazole and Domperidone  by  RP-HPLC method.   The chromatographic conditions were  successfully developed  for  the  separation  of  Lansoprazole and Domperidone by using ... Read More »

Synthesis, Characterization and Antibacterial Activity of some 1,3- Benzthiazol-2-amine derivatives

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India. Abstract Benzothiazole is an aromatic heterocyclic compounds with the general formula C7H5NS which consists of 5 membered hetero cyclic 1, 3 thiazole ring fused to benzene. Benzothiazole is a simple analogues which play a major  role in research which has wide number of ... Read More »

RP-HPLC Method Development and Validation for Simultaenous Estimation of Montelukast and Fexofenadine Hydrochloride in Bulk and Pharmaceutical Dosage Form

L. Nikhil kumar*1, Chandan R.S2 1JSS Academy of Higher Education and Research, Mysore-570015, Karnataka, India. 2Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysore 570015 Karnataka, India. A B S T R A C T A new method was established for simultaneous estimation of Faxofenadine Hydrochloride Hydrochloride and Montelukast by RP-HPLC method.  The ... Read More »

Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Pharmaceutical Dosage Form

D. Hemalatha, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, A.P, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ledipasvir and Sofosbuvir in bulk and its  Tablet dosage form. Chromatogram was run through Std Kromosil C18 (150 x 4.6 mm, 5m) column. Mobile phase containing Buffer 0.01N KH2PO4: Acetonitrile taken ... Read More »

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