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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Research Article Phytochemical Screening and Acute Toxicity Study of Methanol extract of “Cassia tora” Seeds

Raghuram Akinapelli*1, S.N Sri Harsha1, D. Yashwanth Kumar2 Faculty of Pharmacy, PACIFIC University, Udaipur, Rajasthan, India A B S T R A C T Many plant species have been used by most ethnic groups for treating different disease conditions ranging from small infections to skin diseases, asthma, dysentery, malaria and other multiple indications. Herbal Medicine is usage of herbs for ... Read More »

Development and Validation of Analytical Method for the Estimation of Zaltoprofen Using RP- HPLC Method

Kumarraja Jayavarapu*, Dr. S. Parimalakrishnan, Dr. V. D Sundar Research Scholar, Department of Pharmacy, Annamalai University, Tamilnadu – 608002. A  B  S  T  R A C T A simple, sensitive, linear, precise and accurate RP – HPLC method for the estimation of Zaltoprofen was developed and validated. Zaltoprofen [(2RS)-2-(10-oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propionic acid] is a potent NSAID with powerful anti-inflammatory and analgesic effects ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Metformin and Empagliflozin in Bulk and Pharmaceutical Dosage Forms

Dr. Gampa Vijay Kumar*1, P. Sowjanya2 N. Shyam3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T High performance liquid chromatography is at ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Atzanavir and Ritonavir in Pharmaceutical Dosage Forms

Dr. Gampa Vijay Kumar1, B. Sravanthi2, K. Indhumathy3 1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for ... Read More »

Development and Validation of a HPLC Method for Imipenem and Meropenem in Pharmaceutical Dosage Forms

Sanju Srinivas1, Shalindhar2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana Abstract A new method was established for simultaneous estimation of Imipenem and Meropenem by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Imipenem and Meropenem by using Zodiac sil C18 column (4.6×150mm)5µ , flow ... Read More »

Evaluation of Hepatoprotective Activity of Berberis Vulgaris on Azathioprine Induced Oxidative Stress in Rats

Gampa Vijaya Kumar1, Dr. Y. Sridhar2, M.Anitha3 1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor, KGR Institute of Technology and Management, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Kesara, Rangareddy, Telangana, India. Abstract Hepatotoxicity may be predictable or unpredictable. Predictable reactions typically are dose related and occur ... Read More »

A Review on High Performance Capillary Electrophoresis

Dr. M. Sunitha1*, Safa Syed Nasirullah2, Sk. Salma Naheed3, Dr. R. Vani4* 1Principal, Shadan Women’s College of Pharmacy, Hyderabad 2Post-GraduateStudent, Shadan Women’s College of Pharmacy, Hyderabad 3Post-GraduateStudent, Shadan Women’s College of Pharmacy, Hyderabad 4HeadofDepartment, Pharmaceutical Analysis and QA, Shadan Women’s College of Pharmacy, Hyderabad ABSTRACT High performance capillary electrophoresis is a separation technique in which the analysis is separated on ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Determination of Glecaprevir and Pibrentasvir in Its Bulk and Their Pharmaceutical Dosage Forms

MD. Abdul Sattar1*, A. Suneetha2 1University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, 522510,Guntur(Dist), Andhra Pradesh, India 2Depatment  of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur- 522002, Andhra Pradesh, India A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Pioglitazone and Metformin in Bulk and Formulation by Using RP- HPLC

Dr. Gampa Vijay Kumar1*, P. Sowjanya2, Gone Harish3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor KGR Institute of Technology and Management, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for ... Read More »

Evaluation of Anti-Ulcer Activity Lagenaria Siceraria Chloroform Extracts in Pylorus Ligated Rats

Dr. Gampa Vijay Kumar1*, Dr. Y. Sridhar2, M. Prashanth3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor KGR Institute of Technology and Management, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T Peptic ulcer disease is ... Read More »

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