Bacterial Biofilms in Patients with Indwelling Urinary Catheters

Bhanwar Lal Jat¹, Ranjeeta Kumari², Dilip Gena^3
1Department of Botany, Dayanand College MDS University Ajmer Rajasthan India
²Research Scholar, Mewar University, Gangrar, Chittorgarh, Rajasthan, India
³Department of Botany, SPC Government PG College Ajmer Rajasthan India.

 
A B S T R A C T
Bacterial biofilms are responsible for several chronic diseases that are difficult to treat. The aim of this study were following:- (a)Study of incidence rate of biofilm producing organism in tertiary care hospital.(b)Biofilm bacteria show much greater resistance to antibiotics than their free-living counterparts and our interest is to investigate the mechanistic basis of this phenomenon. One potential reason for this increased resistance is the penetration barrier that biofilms may present to antimicrobials yet they were more resistant than their planktonic (free-living) counterpart. This prospective study is conducted in tertiary hospital (Christian medical college and hospital, Ludhiana) and in all age groups. This study was conducted in 4 months. All patients who required surgery and urocatheter tip for more than >7 days are eligible. The incidence of this in tertiary care hospital is 78% initially. Sample received 48 from which 27 are positives, producing biofilms. Rate of biofilm producing organisms are increases very fastly. But it can be reduced by various preventive strategies. Though, its difficult to implement all strategies in a specific hospital set up, but efforts can lead to save life of patients.
Keywords: Bacterial Biofilms, Catheter-associated Urinary tract infection (CAUTI)