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About author Abhilash A*, Prabhu Raj KJ, Hemalatha, Gopi Krishna B.M, Dr. Hindustan Abdul Ahad B. Pharmacy, Balaji College of Pharmacy, Anantapur, AP, India E-mail: [email protected] Abstract The petroleum ether, chloroform and methanol crude extracts of the two different plant parts (leaves andbark) of Mirabilis jalapa (Nyctaginaceae)were screened for cytotoxicity by brine shrimp lethality bioassay and thecrude methanol extract of ... Read More »

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: [email protected] ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the heterocyclic found ... Read More »

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the ... Read More »

About author : Ramesh Dhani Dept. of  Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: A great number of drugs are heterocyclic compounds, mostly are of synthetic origin, few have obtained from natural resources which include alkaloids, xanthines, cardiac glycosides, vitamins and several antibiotics. Heterocyclic derivatives having two nitrogen atoms oriented in, 1-3 position are endowed with wide spectrum of ... Read More »