El Houssine Mabrouk and Abdelilah El Hallaoui
Laboratory of Organic Chemistry, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco
A B S T R A C T
The title compound, Methyl 2-benzamido-2-(N-benzyl N-methylamino) acetate was synthesized in high yield by N-alkylation reaction between methyl α-bromo glycinate or methyl α-azido glycinate N-benzoylated and N-benzyl-N-methylamine in different solvents in the presence of various bases. The structure of this product was established on the basis of NMR spectroscopy (1H, 13C), and MS data.
Keywords: Amine, N-alkylation, α-Amino acids, Methyl α-azido glycinate, methyl α-bromo glycinate.