Monday , 21 October 2019

Synthesis of the new carboxylic α,α-diamino acids: 2-benzamido-2-(N-benzyl N-methylamino) acetic acid and 2-benzamido-2-(N-benzyl N-ethylamino) acetic acid

El Houssine Mabrouk*
Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco

A B S T R A C T
We reported here the synthesis of new α,α-diamino acids derivatives, as  2-benzamido-2-(N-benzyl N-methylamino) acetic acid and 2-benzamido-2-(N-benzyl N-ethylamino) acetic acid through alkaline hydrolysis reaction of corresponding N-benzoylated methyl α,α-diamino esters. The structure of these products were established on the basis of NMR spectroscopy (1H, 13C), and MS data.

Keywords: α,α-Diamino esters; α,α-diamino acids; alkaline hydrolysis reaction.

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