Synthesis and Antimicrobial Evaluation of Some Novel Chalcones and Pyrazoles from Cyclic Imides under microwave irradiation

Prashant P. Chaudhari¹ and Shankarsing S. Rajput^2*
1DepartmentofChemistry, J.J.T. University, Jhunjhunu, Rajasthan, India
²DepartmentofChemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India

A B S T R A C T
A novel class of chalcones and pyrazoles has been prepared by using neutral alumina; under microwave activation and solvent free reaction condition. The compounds were screened for antimicrobial activity against bacterial strains gram positive bacteria Staphylococcus aureus, Bacillus subtilis and gramnegativebacteria Escherichia coli, Pseudomonas aeruginosa and two fungal strains Candida albicans and Aspergillusniger. Some of the compounds exhibited significant inhibitory activity against the microbial strains.
Keywords: Chalcones, Pyrazoles, Cyclic imides, Antimicrobial activities