Friday , 23 October 2020

MEDICINAL CHEMISTRY OF BIOACTIVE NATURAL PRODUCTS

Medicinal Chemistry of Bio-active Natural Products
XIAO-TIAN LIANG
WEI-SHUO FANG
Medicinal chemistry has evolved from the chemistry of bioactive compounds in early days to works at the interface of chemistry and biology nowadays. Medicinal Chemistry of bioactive natural products spans a wide range of fields, including isolation and characterization of bioactive compounds from natural sources, structure modification for optimization of their activity and other physical properties, and total and semi-synthesis for a thorough scrutiny of structure activity relationship (SAR). In addition, synthesis of natural products also provides a powerful means in solving supply problems in clinical trials and marketing of the drug, for obtaining natural products in bulk amounts is often very difficult.

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