K. Jyothsna Jayaraju*, Y. Meenakshi, R. Renuka Devi, P. Sravani, K. Murali Krishna, R. Leela
Dr. K.V. Subba Reddy Institute of Pharmacy, Dupadu, Kurnool-518218, Andhra Pradesh, India
A B S T R A C T
Objective: The present study is aimed to evaluate the in-vitro anti-diabetic and anti-arthritic activity of hydro ethanolic extract of whole plant of Cynodon dactylon. Methods: Non-enzymatic glycosylation of hemoglobin method, Glucose uptake in yeast cells method, and Alpha-amylase inhibition assay method were performed for in-vitro anti-diabetic activity using metformin as standard drugs. Inhibition of protein denaturation method using diclofenac as a standard for in-vitro anti-arthritic activity. Results: The concentration of 10mg/ml of hydro ethanolic extract of plant material showed the maximum results as compared to standard drugs used. Conclusion: As per the results obtained in the present investigation indicates that the hydro ethanolic extract of whole plant of Cynodon dactylon is having potential anti-diabetic and anti-arthritic activity.
Keywords: Cynodon dactylon, Anti-diabetic, Anti-arthritic, Diclofenac sodium, Metformin.