Dr. Gampa Vijaya Kumar*1, S. Raju2, J. Sridhar2
1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
A B S T R A C T
The present study is to evaluate the effect of Caserua sylvestr is Methanolic Extract and Phenolic Extracts on plasma lipid levels in Triton -X-100 induced hyperlipidemic rats. Major complication of hyperlipidemia is atherosclerotic heart disease, heart attack and heart stroke, but atherosclerosis is primary cause of death. Developing countries are reliant on medicinal plants as their main source of treatment for diseases. As Caserua sylvestris have the native habitat the production is more so it is locally available cost effective with no side effects. As Caserua sylvestrisis cost effective and beneficiary in metabolism of cholesterol, so it has been taken in to consideration in order “To evaluate Anti-hyperlipidemic activity of Methanolic Extract and Phenolic Extracts of Caserua sylvestrisin triton X -100 induced hyperlipidemic rats”. The results concluded that PEBM (500 mg/kg) have definite antihyperlipidemic activity in Triton X-100 induced hyperlipidemic model and which is equipotent activity when compared with Atorvastatin treated groups. Further studies on this extract may lead to identify the possible mechanism of action and isolation of active principle from the same.
Keywords: Caserua sylvestris, antihyperlipidemic, Atorvastatin