Monday , 18 February 2019

Evaluation of Anti-Hyperlipidemic Activity of Methanolic Extract of Sesbania Grandiflora in Wistar rats and Observation on Heart rate and Body weight

Dr. Gampa Vijay Kumar*1, Mr. Murali Sollu2, Ama Sneha Sai3
1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.

A B S T R A C T
Major complication of hyperlipidemia is atherosclerotic heart disease, heart attack and heart stroke, but atherosclerosis is primary cause of death. Developing countries are reliant on medicinal plants as their main source of treatment for diseases. As Sesbania grandiflora have the native habitat the production is more so it is locally available cost effective with no side effects. As Sesbania grandiflora is cost effective and beneficiary in metabolism of cholesterol22, so it has been taken in to consideration in order “To evaluate Anti-hyperlipidemic activity of Methanolic Extracts of Sesbania grandiflora in triton X -100 induced hyperlipidemic rats of the respective extracts and the final results showed that this plant shows the hyperlipidemic activity and also shows minimal side effects towards the liver and cardiac muscle tissues.
Keywords: Sesbania grandiflora, hyperlipidemic activity, atherosclerotic heart disease

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