M. Krishnaveni*, AV.Chandana, V.Shanmugam, P.Prakash, S.Sandeep, KV.Radhika
Department of Pharmaceutics, Narayana Pharmacy College, Nellore, Andhra Pradesh, India.
Department Of Pharmaceutics, Sri Padmavathi School Of Pharmacy, Thirupathi, Andhra Pradesh, India.
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Bioadhesive formulations have a wide scope of application for both systemic and local effects of drugs. The mucosa is relatively permeable, well supplied with both vascular and lymphatic drainage. Various drug delivery systems are their which uses the oral mucosa as a drug delivery site such as fast dissolving tablets, orodissolving films, fast caps, buccoadheshive film and tablets, chewing gums etc. Buccal patches are evaluated in terms of Physical characteristics of patches, Physical appearance, Surface texture, Thickness uniformity of films, Uniformity of weight of patches, Swelling studies, Invitro biadhesion measurement, Percentage moisture loss, Surface pH, Folding Endurance, Content Uniformity of Patches, Invitro release studies, Exvivo buccal permeation study .
Key words: bioadhesion, polymer, oral mucosa, buccal film