Govind Shukla*, Nagalakshmi Yaparthy, C.J. Sampath Kumar
Lactonova Nutripharm (P) Ltd, Makers of Astashine Silver capsules, IDA Mallapur, Hyderabad, Telangana, India-500 076.
A B S T R A C T
Astaxanthin is a xanthophyll carotenoid present in microalgae, fungi, complex plants, seafood, flamingos and quail. It is an antioxidant with anti-inflammatory properties and as such has potential as a therapeutic agent in atherosclerotic cardiovascular disease. Experimental studies demonstrated that astaxanthin protects the myocardium. In a randomized, double blind study on humans it was shown that astaxanthin decreased the low-chronic inflammation by reducing oxidative stress. Earlier studies have confirmed that astaxanthin reduces inflammation by inhibiting activation on the transcription factor NF-kB. Due to astaxanthin’s ability to protect cells from oxidation and its anti-inflammatory capacity, astaxanthin has potential to prevent the development of metabolic diseases. L-carnitine is a necessary cofactor for mitochondrial function, stimulating oxidative metabolism of glucose and fatty acids particularly under conditions of ischemia. L-carnitine protects against ischemiainduced myocardial dysfunction and has been demonstrated to improve cardiac function and exercise performance in patients with angina, myocardial infarction, and heart failure. L-carnitine can decrease frequency of angina attacks; reduce deleterious cardiac remodeling and arrhythmias, and improve survival after MI; and decrease symptoms of CHF while increasing long term survival. L-carnitine also benefits peripheral vascular disease. This article reviews the current available scientific literature regarding the effect of astashine silver capsules on the cardiovascular health.
Keywords: Astashine silver capsules, cardiovascular Health.