Thursday , 29 June 2017

A Comparative Study on the Affect of Aqueous Film Coating on Ascorbic Acid and Caffeine Tablets under Specific Process Parameters

MD Abul Haider Shipar*
Toronto Institute of Pharmaceutical Technology, Toronto, Ontario, Canada M1P 4X4.

A B S T R A C T
Ascorbic acid (81mg) and caffeine (65mg) tablets have been produced by standard procedure. The uncoated tablets have been coated by using the specific aqueous film coating formulation under the specified coating variables during the coating process to observe the affect of the formulation on the tablet properties. To achieve the specified weight gain with the formulation containing HPMC E6, propylene glycol, FD&C Yellow # 5 and deionised water, ascorbic acid tablets take more time than caffeine tablets. The coating process has been found taking more time for ascorbic acid tablet than caffeine tablet. For both of ascorbic acid and caffeine tablets, the disintegration time increases after coating with the formulation, which has been found more for ascorbic acid tablets than caffeine tablets.

Keywords: Aqueous film coating, Ascorbic acid tablet, Caffeine tablet, Specific process parameters.

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