Tuesday , 7 July 2020

Tag Archives: RP-HPLC

Development and Validation of Stability indicating HPLC method for simultaneous estimation of `Metformin and Ertugliflozin

P. Harsha Hruditha*, Dr. P. Jayachandra Reddy Krishna Teja Pharmacy College, Renigunta Road, Tirupati, Andhra Pradesh 517506 ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ertugliflozin and Metformin in Tablet dosage form. Chromatogram was run through phenomenex c18 150 x 4.6 mm, 5m. Mobile phase containing Buffer: Acetonitrile taken in the ratio 60:40 was ... Read More »

Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Pregabalin and Methylcobalamin in Formulation by QBD Approach

Aasadi Balaji*, G. Dharmamoorthy, G. Aruna, KV Nanda Kumar, P. Jaya Chandra Reddy Krishna Teja Pharmacy College, Chadalawada Nagar, Renigunta Road Tirupati-517506 ABSTRACT By considering the current regulatory requirement for an analytical method development, a simple, precise, accurate, linear and rapid Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method for the simultaneous quantitative estimation of Pregabalin 75mg and Methylocobalamin 750µg ... Read More »

Analytical Method Development and Validation of Paclitaxel Pharmaceutical Dosage Forms by RP-HPLC

K. Nithiyananthan1 K.V.S Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur. 2Principal, Rahul Institute of Pharmaceutical Sciences and Research, Chirala. ABSTRACT A simple, precise, accurate RP-HPLC method was developed and validated for the estimation of Paclitaxel in pharmaceutical dosage forms. An Agilent column (4.6×150mm) 5µ, flow rate was 1.0 ml/min, mobile phase ratio was Methanol: Phosphate buffer (60:40% v/v), detection wavelength ... Read More »

Analytical Method Development and Validation of Palbociclib in Its Pure Dosage Forms

K. Nithiyananthan1*, K.V.S Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur. 2Principal, Rahul Institute of Pharmaceutical Sciences and Research, Chirala. A  B  S  T  R A C T A simple, rapid, and robust RP-HPLC method have been developed and validated to measure Palbociclib at single wavelength (320nm). An isocratic elution of samples performed on YMC C18 column (4.6×150mm) 5µ, flow rate ... Read More »

RP- HPLC Method Development and Validation for the Simultaneous Estimation of Donepezil and Memantine

S. Uday Venkata Sai Kumar*, G. Dharma Moorthy1, N. Sujani2, S. Veera Sekhar3, E. Vijay Kumar4 *Krishna Teja Pharmacy College, Tirupati, A.P., India 1Associate Professor, Krishna Teja Pharmacy College, Tirupati, A.P., India 2,3,4 Assistant Professor, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P., India A  B  S  T  R A C T A new method was established for the simultaneous estimation ... Read More »

Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Glecapravir and Pibrentasvir in API and Marketed Formulation

Y. Suresh*1, Sanjay Kumar Jain2 1Safa College of Pharmacy, Kurnool, Andhra Pradesh, India 2Department of Pharmaceutical Analysis, Bundelkhand University, Jhansi, U.P, India A B S T R A C T The present attempt was made to development of validated RP-HPLC method for the simultaneous estimation Glecapravir and Pibrentasvir in bulk and pharmaceutical dosage form. The chromatographic separation was carried on ... Read More »

RP-HPLC method for the Simultaneous estimation of Ezitimibe and Simvastatin in bulk and it’s tablet dosage form

C. Karuppasamy*1, Sanjay Kumar Jain2 1Safa College of Phrmacy, Kurnool, Andhra Pradesh, India 2Department of Pharmaceutical Analysis, Bundelkhand University, Jhansi, U.P, India A B S T R A C T The present attempt was made to development and validation of new RP-HPLC method for the simultaneous estimation of Ezitimibe and Simuvastatin in bulk and tablet dosage form. The chromatographic separation ... Read More »

Simultaneous RP-HPLC method for the estimation of Clopidogrel and Atorvastatin in bulk and its tablet dosage form

C. Karuppasamy*1, Sanjay Kumar Jain2 1Safa College of Pharmacy, Kurnool, Andhra Pradesh, India 2Department of Pharmaceutical Analysis, Bundelkhand University, Jhansi, U.P, India A  B  S  T  R A C T The aim of present research work simple, precise, accurate and robust RP-HPLC method for the simultaneous estimation of Clopidogrel and Atorvastatin in bulk and tablet dosage form. The chromatographic separation ... Read More »

Simultaneous RP-HPLC Method for the Quantification of Durnavir and Ritonavir in bulk and it’s Pharmaceutical Dosage form

Y. Suresh*1, Sanjay Kumar Jain2 1Safa College of Pharmacy, Kurnool, Andhra Pradesh, India 2Department of Pharmaceutical Analysis, Bundelkhand University, Jhansi, U.P, India A  B  S  T  R A C T The aim of present research work to develop and validated RP-HPLC method for the simultaneous estimation Durnavir and Ritonavir in bulk and pharmaceutical dosage form. The chromatographic separation was achieved ... Read More »

Development of Simple, Reliable, Rugged, Specific and Stability Indicating HPLC Methods for Quantification of Impurities in Dapagliflozin

R. Suresh1*, Dr. Satyavir Singh 2, K. Subhash Chander Reddy3 1Research Scholar, Department of Science, OPJS University, Churu, Rajasthan. 2Department of Science, OPJS University, Churu, Rajasthan. 3Director Honour lab R&D, Bonthapalli, Hyderabad, Telangana. A B S T R A C T The aim of present research work method development and validation for the quantification of Dapaliflozin and it impurities in ... Read More »

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