Thursday , 23 January 2020

Tag Archives: RP-HPLC

Analytical Method Development and Validation for Simultaneous Estimation of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage form by RP-HPLC

N. Kalpana Devi*1, Tirupathi Rao Velamala2, D.S.S.N.Neelima3 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Sulphadoxine and Pyrimethamine, in its pure form as well as in ... Read More »

Stability indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Metformin and Teneligliptin in Pharmaceutical Formulation

Ramesh Dhani*, V. Haribaskar, J. Priyanka Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Teneligliptin in pharmaceutical dosage form. Chromatogram was run through ODS2 C 18 (4.6 x 200mm, 10.0µm)column.   Mobile phase containing ... Read More »

Development and Validation of Analytical Method for the Estimation of Zaltoprofen Using RP- HPLC Method

Kumarraja Jayavarapu*, Dr. S. Parimalakrishnan, Dr. V. D Sundar Research Scholar, Department of Pharmacy, Annamalai University, Tamilnadu – 608002. A  B  S  T  R A C T A simple, sensitive, linear, precise and accurate RP – HPLC method for the estimation of Zaltoprofen was developed and validated. Zaltoprofen [(2RS)-2-(10-oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propionic acid] is a potent NSAID with powerful anti-inflammatory and analgesic effects ... Read More »

Development and Validation of a HPLC Method for Imipenem and Meropenem in Pharmaceutical Dosage Forms

Sanju Srinivas1, Shalindhar2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana Abstract A new method was established for simultaneous estimation of Imipenem and Meropenem by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Imipenem and Meropenem by using Zodiac sil C18 column (4.6×150mm)5µ , flow ... Read More »

Development of New Validated Stibility Indicating RP-HPLC Method for the Simultaneous Estimation of Rosuvastatin and Aspirin in Bulk and Pharmaceutical Dosage Form

Ramesh Dhani*, V. Haribaskar, G. Guramjyothi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India Abstract Simple precise and accurate method was developed for the estimation of   Rosuvastatin and Aspirin. The mobile phase consisting of 0.01N Phosphate buffer 32 as mobile phase A and acetonitrile 68 as mobile phase B gave retention time for Rosuvastatin and Aspirin ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Determination of Glecaprevir and Pibrentasvir in Its Bulk and Their Pharmaceutical Dosage Forms

MD. Abdul Sattar1*, A. Suneetha2 1University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, 522510,Guntur(Dist), Andhra Pradesh, India 2Depatment  of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur- 522002, Andhra Pradesh, India A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ceftolozane and Tazobactam in Its Bulk and Pharmaceutical Dosage Forms

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, R. Mahesh Babu3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Dolutegravir and Rilpivirine in Its Pure and Pharmaceutical Dosage Form

Sonalika Patro1, Ramesh Dhani1*, V. Haribaskar1, K. Sivasankar2 1Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh 2Department of Chemical Engineering, SVU University, Tirupathi, Andhra Pradesh ABSTRACT A Simple Rapid, Precise and Accurate High Performance Liquid Chromatography method was Developed and Validated for Determination of Dolutegravir and Rilpivirine in Bulk and Pharmaceutical Dosage Form. The Method Development was ... Read More »

Method Development and Validation for the Assay of Nebivolol Tablets by using RP-HPLC

1N. Kalpana Devi*, 2Pradeep Reddy, 3D.S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3 Vikas Institite of Pharmaceutical Sciences, Rajahmundary ABSTRACT A simple, precise, and accurate gradient reversed-phase (RP)  high-performance liquid chromatographic (HPLC) assay method was developed and validated for determination of nebivolol in tablet dosage forms. gradient RP-HPLC separation was achieved on a Phenomenex, kinetex ... Read More »

Development and Validation of Tramadol Hydrochloride Capsules by RP-HPLC Method

M. Murugeshwari*, T. Senthil kumar, N. Venkateshan Department of Pharmaceutical Analysis, Arulmigu Kalasalingam College of Pharmacy, Anandnagar, Krishnankoil – 626 190, Tami Nadu. A B S T R A C T A simple, fast and precise reverse phase high performance liquid chromatography method was developed for the determination of Tramadol Hydrochloride in capsules by using HiQ W C18(250mm×4.6mm, i.d., 5µ) ... Read More »

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