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Tag Archives: RP-HPLC

Development of New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Rosuvastatin and Aspirin in Bulk and Pharmaceutical Dosage Form

G. Gurum Jyothi, Ramesh Dhani*, V. Hari Baskar, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Rosuvastatin and Aspirin. The mobile phase consisting of 0.01N Phosphate buffer 32 as mobile phase A and ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form

B. Swathi, V. Hari Baskar*, Ramesh Dhani, M. Bharathi, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformin, Pioglitazone and Glimepiride in Combined Tablet Dosage Form by using RP-HPLC

M.D. Fiaz*, Dr. R. Vani, Dr. Iffath Rizwana Post graduate student, Deccan School of Pharmacy, Hyderabad, Telangana, India. University of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Metformin, Pioglitazone and Glimepiride in Tablet dosage form by using RP-HPLC method. Methods: ... Read More »

Development and Validation of RP-HPLC Method for Simultaneous Determination of Donepezil and Memantine in their Tablet Dosage Forms

Srinivas Ganta*, Vidyadhara S Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur-522018, Andhra Pradesh, India. A B S T R A C T A simple, accurate and specific RP-HPLC method has been developed and validated for the simultaneous estimation of Memantine (MEM) HCl and Donepezil (DON) HCl in bulk and pharmaceutical dosage form. Chromatographic separation was achieved on Symmetry C18 ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Glibenclamide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Ramanjaneyaulu*, Devika Subrramaniyan.G, Ramesh petchi Rajendran Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Glibenclamide in bulk and Pharmaceutical dosage form. The separation was acheived by using C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio ... Read More »

Evaluation of Analgesic Activity and Anti-Epileptic Activity of Ether Leaf Extract of Guggul

K. N. S. Karthik, Konda Ravi Kumar* Department of Pharmaceutical Chemistry, Hindu college of Pharmacy, Amaravathi Road, Guntur. Andhra Pradesh, India. A B S T R A C T Commiphora mukul is a flowering plant in the family Burseraceae. It is a shrubor small tree, attaining maximum height of 4 m, with thin paper y bark and thorny branches. The ... Read More »

Method Development and Validation of Mycophenolate Mofetil by RP-HPLC

Rubina Kauser, M. Mushraff Ali Khan, Airaj Mahajabeen, Farhana Shaheen, Salma Begum MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »

Method Development and Validation of Metformin in Pure and Its Tablet Dosage Form by using RP-HPLC

Dr. Hareesh Dara, Meesa Rajendar, Dr. D Siva Dinesh St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T High Performance Liquid Chromatography is now one of the most powerful tools in analytical chemistry. It has the ability to separate, identify, and quantitative the compounds that are present in any sample that can ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Method Development and Validation of Olodaterol and Tiotropium by RP-HPLC Method

Farhana Shaheen*, Salma Begum, Rubina Kauser, Airaj Mahajabeen, MD Muzammil Hassan MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reverse phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »

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