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Tag Archives: RP-HPLC

Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Determination of Glecaprevir and Pibrentasvir in Its Bulk and Their Pharmaceutical Dosage Forms

MD. Abdul Sattar1*, A. Suneetha2 1University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, 522510,Guntur(Dist), Andhra Pradesh, India 2Depatment  of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur- 522002, Andhra Pradesh, India A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ceftolozane and Tazobactam in Its Bulk and Pharmaceutical Dosage Forms

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, R. Mahesh Babu3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Dolutegravir and Rilpivirine in Its Pure and Pharmaceutical Dosage Form

Sonalika Patro1, Ramesh Dhani1*, V. Haribaskar1, K. Sivasankar2 1Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh 2Department of Chemical Engineering, SVU University, Tirupathi, Andhra Pradesh ABSTRACT A Simple Rapid, Precise and Accurate High Performance Liquid Chromatography method was Developed and Validated for Determination of Dolutegravir and Rilpivirine in Bulk and Pharmaceutical Dosage Form. The Method Development was ... Read More »

Method Development and Validation for the Assay of Nebivolol Tablets by using RP-HPLC

1N. Kalpana Devi*, 2Pradeep Reddy, 3D.S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3 Vikas Institite of Pharmaceutical Sciences, Rajahmundary ABSTRACT A simple, precise, and accurate gradient reversed-phase (RP)  high-performance liquid chromatographic (HPLC) assay method was developed and validated for determination of nebivolol in tablet dosage forms. gradient RP-HPLC separation was achieved on a Phenomenex, kinetex ... Read More »

Development and Validation of Tramadol Hydrochloride Capsules by RP-HPLC Method

M. Murugeshwari*, T. Senthil kumar, N. Venkateshan Department of Pharmaceutical Analysis, Arulmigu Kalasalingam College of Pharmacy, Anandnagar, Krishnankoil – 626 190, Tami Nadu. A B S T R A C T A simple, fast and precise reverse phase high performance liquid chromatography method was developed for the determination of Tramadol Hydrochloride in capsules by using HiQ W C18(250mm×4.6mm, i.d., 5µ) ... Read More »

Simultaneous Estimation of UV Spectroscopy and Method Development and Validation for Lansoprazole and Domperidone by RP-HPLC

Sanju Srinivas1, Marium Nazneen2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T A new method was established for simultaneous estimation of Lansoprazole and Domperidone  by  RP-HPLC method.   The chromatographic conditions were  successfully developed  for  the  separation  of  Lansoprazole and Domperidone by using ... Read More »

Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Pharmaceutical Dosage Form

D. Hemalatha, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, A.P, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ledipasvir and Sofosbuvir in bulk and its  Tablet dosage form. Chromatogram was run through Std Kromosil C18 (150 x 4.6 mm, 5m) column. Mobile phase containing Buffer 0.01N KH2PO4: Acetonitrile taken ... Read More »

Simultaneous Estimation Method Development and Validated on Timolol Maleate and Brimonidine Tartrate by Using HPLC

1N. Kalpana Devi*, 2Sindhu Priya Mattepalli, 3D. S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad Telangana State 3Vikas Institite of Pharmaceutical Sciences – Rajahmundary ABSTRACT A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Timolol Maleate and Brimonidine Tartrate, in its pure form as well as in tablet dosage ... Read More »

Development and Validation of RP HPLC Method for Simultaneous Estimation of Netupitant and Palonosetron in Pharmaceutical Dosage Form

Dr. Gampa Vijay Kumar1*, B. Sravanthi2, N. Gayathri Aparna3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. A  B  S  T  R A C T On the basis of experimental results, ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Acetaminophen and Tramadol Hydrochloride in Tablet Dosage Form

S. Pavani, V. Hari Baskar*, B. Prathap, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore, A.P, India ABSTRACT A simple, Accurate, rapid and precise method was developed for the simultaneous estimation of the Acetaminophen and Tramadol hydrochloride in Tablet dosage form. The chromatogram was run through. Spurcil, column (4.6 x 150mm, 5µ).Mobile ... Read More »

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