Monday , 20 May 2024

Protective effect of withania somnifera on 1, 4-dioxane and trichloro ethylene-induced changes in catalase activity in erythrocytes of in-vitro goat haemic system

Devendra Pratap Singh1*, Girendra Kumar Gautam1, Amit Kumar Mishra1, Poonam Gupta2, Ankit Saini3
1Bhagwant Institute of Pharmacy, Muzaffarnagar, India
2Krishna College of Science and Information Technology, Bijnor, India
3Krishna College of Pharmacy, Bijnor, India

Today, numbers of chemicals have been registered for use in the USA and new are being introduced as agricultural chemicals, personal care products, industrial chemicals etc. The atmosphere is being polluted frequently with varieties of chemical substances daily during their manufacture, distribution, use and disposal. The chronic exposure of animals and humans to toxic environmental pollutants is a global health concern. 1,4-dioxane and trichloroethylene are the two of such pollutants which affects can vital functions of human and animal body.  The present study reveals the effects of 1,4-Dioxane and Trichloroethylene on catalase present in erythrocytes and assess the protective effect of Withania somnifera root extract on catalase level and activity of erythrocytes of in-vitro goat haemic system.
Key words: Withania somnifera, 1,4- Dioxane, Trichloroethylene, Catalse

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