Evaluation of Survival Rate in Patients with Diabetic Foot Ulcer with Comorbid Conditions in Tertiary Care Hospital

Sk. Salma Sultana¹*, Sk. Musfira Kauser², S. Sirisha Reddy³, Md. Muddasseer⁴, K. Venkata Krishna⁵ Dr.G.V.Prakash⁶, Dr. Kudipudi Harinadha Baba^7
1*Department of Pharmacology, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002.
²Pharm D, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002.
³Pharm D, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002.
⁴Pharm D, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002.
⁵Pharm D, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002.
⁶Department of General Surgery, Narayana Medical College, Chinthareddypalem, Nellore -524002.
⁷Department of Pharmaceutical Analysis, Narayana Pharmacy College, Chinthareddypalem, Nellore – 524002.

A b s t r a c t
Aim: Diabetic foot ulcer is the most common complication of diabetic foot ulcer and has a significant life threatening impact on the patients especially patients with other comorbidities predominantly diabetes mellitus. Therefore, the purpose of this study is to estimate the survival rate in various patients suffering from DFU associated with comorbidities such as hypertension, Diabetes Mellitus, Cardiovascular diseases and other complications.Materials and methods: An observational retrospective cohort study was conducted on approximately 120 patients in general surgery department of Narayana medical hospital over a period of 6 months October 2022 to May 2023. Ethical clearance also has been acquired from the Institutional review committee at Narayana Medical College. Results: Among the 120 patients observed during the study, DFU along with only DM comorbidity were recorded in highest number i.e., 31 (35.83%). 16.66% and 11.66% DFU patients were suffering from DM along with hypertensions and CVS diseases respectively. Maximum no.of deaths were recorded in DFU patients with CVS diseases (43.75%) when compared to other comorbid conditions. Based on the data collected, 86.6% survival risk probability was observed in patients with CVS diseases indicating lower survival chances. Conclusion: Based on the available data collected during the study, after assessing the data and acquiring the results, it was concluded that patients with DFU associated with CVS diseases comorbidities has lower survival based on over survival rate.
Keywords: Diabetic foot ulcer, Survival Rate, Retrospective cohort study, comorbid conditions