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Tag Archives: Bile acids

ANTIULCER ACTIVITY OF TERMINALIA CHEBULA IN PYLORIC LIGATURE INDUCED GASTRIC ULCERS

About author Dimak Chand Sahu*, Anil Kumar Rai, Sanjay J. Ingle, Ravi Prakash Department of Pharmacology SIRT, Bhopal, Madhya Pradesh, India Malhotra College of Pharmacy, Bhopal, Madhya Pradesh, India E-mail : [email protected] ABSTRACT Various factors that have been implicated in the pathogenesis of gastric ulcers are an increase in gastric acid secretion, pepsin activity and oxidative stress in the gastric ... Read More »

ABSORPTION AND DRUG DEVELOPMENT (Solubility, Permeability, and Charge State)

ALEX AVDEEF This is useful for the practicing pharmaceutical scientist involved in absorption–distribution–metabolism–excretion measurements who needs to communicate with medicinal chemists persuasively, so that newly synthesized molecules will be more ‘‘drug-like.’’ ADME is all about ‘‘a day in the life of a drug molecule’’ (absorption, distribution, metabolism, and excretion). Specifically, this book attempts to describe the state of the art ... Read More »

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