Monday , 6 February 2023

Tag Archives: Benzimidazole

Synthesis of Some Novel Benzimidazole Derivatives & Evaluation of Their Antibacterial Activity

Jayakumar.A*, Ramesh Dhani, Sindhu.P, Ayesha.K, Keerthi. V, Rajeswari.P, Sukanya.P, Vijayadurga.P, Department of Pharmaceutical Chemistry, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District-524 346 ABSTRACT Benzimidazoles are heterocyclic compounds in which benzene is fused with five membered ring containing two hetero atoms. Both hetero atoms are nitrogen (N), which are present at non-adjacent position. It has broad spectrum ... Read More »

Cycloaddition involving activated isothiocyanate: Synthesis and antimicrobial activities of thiazine, pyrimidine and pyridine derivatives

Amira A.Ghoneim*, Mohamed G.Assy, Enaiat K.Mohamed, Islam Ragab Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt A B S T R A C T Aniline was added to acylisothiocyante [1] to produce 1,3-thiourea derivative [2]. Allowing compound [2] to react with sodium ethoxide, at room temperature resulted in thiazine cyclization affofding [3]. Refluxing 2 in sodium ethoxide afforded the ... Read More »

SYNTHESIS AND CHARACTERIZATION OF ETHYL (1H-BENZIMIDAZOL-2-YL- SULFANYL) ACETATE

About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5, 6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12. Diversity ... Read More »

Synthesis and Characterization of 2-[1H- benzimidazole-2yl-sulfanyl]-N-[(E)-(4-methoxy phenyl) methylidene] Aceto hydrazide

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India *E-mail: dhanipharmachem@gmail.com Content : The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Diversity of biological response profile has attracted considerable interest of several researchers across the globe to explore thisskeleton for its assorted therapeutic significance. 1.Synthesis ... Read More »

ANTIMICROBIAL SCREENING OF SOME NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

About Author Ramesh Dhani  Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India. *E-mail: dhanipharmachem@gmail.com ABSTRACT: Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, heterocyclic structures form the basis of many pharmaceutical, agrochemical and veterinary products. The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Diversity of ... Read More »

Scroll To Top