Bhaskar A* and Veerapuram Kumar Reddy
Department of Pharmaceutics, Seshachala College of Pharmacy, Puttur-517583, Chittoor, A.P., India.
In the present study, Oral dispersible Tablets were designed with a view to enhance patient compliance. In this method, the Hordeum Vulgare Hull, cross carmellose sodium, and sodium starch glycolate were used as superdisintegrants (4 and 6%), along with microcrystalline cellulose and mannitol, to enhance mouth feel. The prepared batches of tablets were evaluated for hardness, friability, drug content uniformity, wetting time, water absorption ratio and invitro dipersion time. Based on the in vitro dispersion time, the formulations were tested for the in vitro drug release patterm. Tablets having Hordeum Vulgare Hull showed the release profile comparable to those tablets having sodium starch glycolate and cross carmellose sodium.
Keywords: Oral dispersible tablet, Hordeum Vulgare Hull, In vitro dissolution study, sodium starch glycolate.