K. Kalpana Devi1*, Chandrika Dontha2, D.S.S.N. Neelima3
1,2Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State.
3Vikas Institite of Pharmaceutical Sciences, Rajahmundary.
A B S T R A C T
Ulcer is a major global problem affecting day to day life in humans and the causative factors being unavoidable such as stress, use of non steroidal antiinflammatory drugs (NSAID’s) etc. Evaluation of Methanolic Extract of Seed of Macuna Pruriens For Antiulcer Activity. In this study we observed that, methanol and extract of macuna provides significant antiulcer effect against gastric ulcers in rats. The antiulcer activity of extracts may be a arrtributed to their flavanoids content and antioxidant property. The extract of the plants macuna produced significant reduction in the ulcer index, ulcer score, when compared to control. The preliminary phytochemical analysis of macuna pruriens extract showed the presence of flavanoids, saponins and alkaloids.
Key Words: Macuna, Anti-ulcer, flavanoids.