Urmila Choudhary*1, ND Soni1, Rajnee1, Raaz K Maheshwari2
1Department of Physiology, SN. Medical College, Jodhpur, Rajasthan, India.
2Department of Chemistry, SBRM Govt. PG College, Rajasthan, India
Insulin plant (Cogtus Igneus) is a medicinal plant and capable of having Magic Cure for Diabetes. Leaf of this herbal plant helps to build up insulin by strengthening β-cells of pancreas in the human body thus popularly known as “Insulin plant” in India. In view of the above aspect the present review provides profiles of this plant with hypoglycemic properties, available through literature source from various databases with proper categorization according to the parts used, mode of reduction in blood glucose (insulin mimetic or insulin secretagogues activity) and active phytoconstituents having insulin mimetics activity. The review describes some new bioactive drugs and isolated compounds from plants. Thus, from the review majorly, the antidiabetic activity of studied medicinal plant is attributed to the presence of polyphenols, flavonoids, terpenoids, coumarins and other constituents which show reduction in blood glucose levels. The review also delineates the management aspect of diabetes mellitus using this plant and its principles.
Keywords: Phytoconstituents, Blood glucose, Insulin, β-cell, Antidiabetic activity, Metabolic disorder, Herbal medicine, Hypoglycaemic activity, Trace elements