Thursday , 28 March 2024

Assessment of Adverse Drug Reactions (Anti Virals & Anti-Diabetics) in a Teritiary Care Hospital – Nellore

S. Nagabharathi*, Sk. Sadiqa Tanveer, K. Bhargavi, K. Kavya, G. Pramod Kumar, U. Varsha
Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore

A b s t r a c t
Pharmacovigilance target towards signal detection, creating warning, restricting drug use, sometimes withdrawal of drug from market & finally decreasing mortality & risk of ADRs in patients. The present study was conducted in the Department of General medicine, AC Subba Reddy Government Medical College and tertiary care teaching hospital, Nellore, Andhra Pradesh. The study was conducted for four months from December 2022 to March 2023. The study was retrospective, non-interventional and observational type, as a part of routine post-marketing surveillance. On WHO causality scale, causality of maximum ADRs was possible (92.45 %) followed with probable, in line with study of Patel et.al (2015) but in contrary to Gungam et.al (2018). As per Rawlins and Thompson’s classification Type A ADRs account for 48.11 % followed by Type –C (41.51%), type- B and no case of Type –D, E,F. Severity of ADRs as per Hartwig’s scale was found to be of mild category (100%) in line with Gungam et al study. More precise side effects data on these drugs will help in reducing the ADRs burden and ascertain patient safety.

Keywords: Pharmacovigilance, Hartwig’s scale, post-marketing surveillance, ADRs.

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