About author :
P. Jaya Preethi*, K. Sumathi
Department of Pharmacy, Nandha College of Pharmacy and Research Institute,
Koorapalayam Piruvu, Erode, TamilNadu, India.
*E-mail: [email protected]
Kappaphycus alvarezii (syn. K. cottonii) is a species of red alga. It is one of the most important commercial sources of carrageenans, a family of gel-forming, viscosifying polysaccharides. The present paper deals with extraction, phytochemical investigation, anti viral, antioxidant, total phenol content and wound healing activity of red Algae Kappaphycus alvarezi. The algae is processed and it is extracted with ethylacetate and methanol by hot percolation. The extract was subjected to Preliminary Phytochemical Screening for the presence of different chemical groups. The plant contains phytochemicals such as carbohydrates, protein, flavonoids, glycosides, alkaloids and saponins. The methanolic extract is used for wound healing activity (Incision wound model) and it showed significant activity. The algae is now extracted by centrifugation and the extract is used for anti viral (CPE Inhibition assay), anti oxidant (DPPH aand ABTS assay), total phenolic content. The extract is identified by NMR analysis. The results of the three assays of DPPH, ABTS and Total phenolic content are in the agreement in that the RMA extract of Kappaphycus showed an ability to reduce free radicals or oxidative damage. The antioxidant activity of the extract of Kappaphycus is likely to be due to its phenolic contents.
Key words: Kappaphycus alvarezii, anti viral, antioxidant, total phenol content, wound healing activity