Wednesday , 17 August 2022

Anthelmintic activity of the seed of Anethum graveolens

Pankaj Kushwah1*, Nandu Kayande2
1HOD Dept. of Pharmacognosy, Nimar Institute of Pharmacy, Dhamnod, Opp.ITI, Dhar. M.P.454552
2Department of Pharmacology,  Nimar Institute of Pharmacy, Dhamnod, Opp.ITI, Dhar. M.P.454552

ABSTRACT
The aim of present study was to evaluate anthelmintic potential of aqueous extract of Anethum graveolens using Pheretima posthuma as test worm. Three concentrations (10, 25 and 50 mg/ml) of aqueous extract and its various fractions were tested in the bioassay, which involved determination of time paralysis (P) and the time of death (D) of the worms. The results present study indicated that crude aqueous extract significantly demonstrated paralysis and also caused death of worms especially at higher concentration of (100 mg/ml) used as compared reference Albendazole. Allophylus serratus showed the best anthelmintic activity . Thus extracts exhibited anthelmintic activity and could be an inexpensive and readily available source of anthelmintic treatment.
Keywords: Anethum graveolens, Albendazole, Anthelmintic, Pheretima posthuma

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