P.Laxmi*1, Dr. G.Vijayalakshmi2, Dr. V.V. Basava Rao3
1Research Scholar, Department of Pharmaceutical Sciences, University College of Technology, Osmania University, Hyderabad-500007.
2Department of Chemistry, University College of Technology, Osmania University, Hyderabad-500007.
3Department of Chemistry, University College of Technology, Osmania University, Hyderabad-500007.
A B S T R A C T
Topical gels are becoming more popular due to ease of application and better precutaneous absorption. Topical gels are intended for skin application orto certain mucosal surfaces for local action or percutaneous penetration of medicament or for their emollient or protective action. Trans dermal drug delivery systems are a constant source of interest because of the benefits that they afford in overcoming many drawbacks associated with other modes of drug delivery (i.e. oral, intravenous). Microsphere denotes that micrometre in size but the main motto is to deliver the drug and it depends on the routes of administration. Topical delivery of microsphere is one of the most important to deliver the drug into the body. Microsphere can work as a transporter for the drugs in a sustained control release manner. As a result, it clears the potential of the effectiveness of active pharmaceutical ingredients through the barrier of skin by the help of penetration property and vehicle technology of microsphere. In this review, some basic and primitive features of microspheres in the form of topical delivery has been discussed.
Keywords: Topicalgels, Microsphere, surfactant, co-surfactants, penetration.