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PS Pradeep, NM Jagadeesh, HC Kiran Kumar, KM Mahadevan* Department of Post Graduate Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, P. G. Centre, Kadur, Karnataka-577 548, India. A B S T R A C T A milder and efficient method was described for the synthesis of cis-1-(2-(4-(trifluoromethyl) phenyl)-1, 2, 3, 4-tetrahydroquinolin-4-yl) pyrrolidin-2-ones/azepan-2-ones (3a-d, 4a-d) via imino Diels-Alder ... Read More »
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Tag Archives: SAR
SAR Study, Molecular Property and In Silico study of Novel Tetrahydroquinolines bearing Trifluoromethyl Group for Anticancer, Antimalarial, Anti HIV Activities
PS Pradeep, NM Jagadeesh, HC Kiran Kumar, KM Mahadevan* Department of Post Graduate Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, P. G. Centre, Kadur, Karnataka-577 548, India. A B S T R A C T A milder and efficient method was described for the synthesis of cis-1-(2-(4-(trifluoromethyl) phenyl)-1, 2, 3, 4-tetrahydroquinolin-4-yl) pyrrolidin-2-ones/azepan-2-ones (3a-d, 4a-d) via imino Diels-Alder ... Read More »
Synthesis, characterization and in vitro biological evaluation of some new 3-substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists
ABOUT AUTHOR Chandra Sekhar Gudla*1, Madhavan .G.R1, Nagarajan Arumugam2 1Connexios Life Sciences Private Limited, 108/27, 29th main, 23rd cross, BTM Layout – II stage, Bangalore –560076, India 2Department of Pharmaceutical Chemistry, PSG College of Pharmacy, Peelamedu, Coimbatore-641004, Tamilnadu, India Abstract In this letter, the series of 3-(4-aryloxyaryl) propanoic acid compounds design, synthesis, structure–activity relationship (SAR) and the ability to modulate the activity ... Read More »
