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Tag Archives: pyrimidine

Potential Antimicrobial Therapeutic Applications of Coumarine Derivatives: A Review

T. Yunus Pasha*, Shankar M, Vidya A.D Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adhichunchanagi University, B. G Nagar-571448, Nagamangala Taluk, Mandya, Karnataka. A  B  S  T  R A C T Coumarin is a fused heterocyclic compound consists of benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because of their numerous biological activity ... Read More »

Synthesis, Characterization, Biological Evaluation and Docking studies of 2-(benzyl sulfonyl)-5-(3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazole Derivatives

G. Govindu*, D. Rajesh, P. Raveendra Reddy, L.K. Ravindranath Department of chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P-India A B S T R A C T New novel derivatives of 2-((4- substituted benzyl)sulfonyl)-5-(3-(4-( substituted phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazoles  (9a-l as per scheme-I)were prepared by condensation of 2-(4-hydrazinylpyrimidin-5-yl)-5-((4-substituted benzyl)sulfonyl)-1,3,4-oxadiazole (8a-f) with various 4-substituted benzoic acids. The synthon 8a-f were obtained by the refluxing of 2-(4-chloropyrimidin-5-yl)-5-((4-substituted ... Read More »

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