Tuesday , 6 June 2023

Tag Archives: LOD and LOQ

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Glibenclamide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Ramanjaneyaulu*, Devika Subrramaniyan.G, Ramesh petchi Rajendran Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Glibenclamide in bulk and Pharmaceutical dosage form. The separation was acheived by using C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Gemigliptin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Y. Krishna Reddy*, Kedhareshwari, Y. Harikha, V. Harikrishna, Muzahid, K. Gopi Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Metformin and Gemigliptin by using RP-HPLC. The Phosphate buffer was pH 3.0 and the mobile phase was optimized with consists of Methanol: Phosphate buffer ... Read More »

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