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Tag Archives: Docking

In-Silico Structure-Activity Relationship and Molecular Docking Study of Levofloxacin and its Mono substitted Analogues against the Escherichia coli DNA Gyrase

O.A Durojaye*, U. I Njoku, S. Cosmas, E. N Akpan, M. M Ganyam University of Nigeria, Nsukka.  A B S T R A C T Background: Escherichia coli is one of the most frequent causes of many common bacterial infections, including cholecystitis, bacteremia, cholangitis, urinary tract infection (UTI), traveler’s diarrhea, and other clinical infections such as neonatal meningitis and pneumonia. ... Read More »

In-Silico Design & Lead Optimization of Pyrazolo Quinazolines Derivatives using Docking, Virtual Screening Techniques

T. Srivalli*1, Dr. R.Suthakaran2 1Research Scholar, Department of Pharmaceutical Chemistry, JNTU Hyderabad, Telanagana, India. 2Vijaya College of Pharmacy, Hayathnagar, Hyderabad, Telangana, India. A B S T R A C T The pyrazolo quinazolines ring systems bearing various substituents at the C-3 position are widely distributed in nature. Luteolin is a flavanoid derivative, has been reported to have anti cancer, anti ... Read More »

Pharmacophore Design on Renin Inhibitors

S. P. Likitha Rao*1, Anil Middah1, Neeraj Tandan2 1OPJS University, Rajasthan, India 2SARC (Scientific and Applied Research Centre), Hyderabad, India A B S T R A C T The aim of present study was to develop renin inhibitor as anti-hypertensive drug. Selective inhibition of the renin has gained attraction as interesting approach to control hypertension and associated cardiovascular risk factors ... Read More »

In-Silico Analysis of Ketosterol and It’s Binding Possible Interacting Partners in Estrogen Receptor

Ravuri Venkata Rao*1, AVVS Swamy2, Tulasi Narahari3, Harika Boorsu3 1Research Scholar, Department of Biochemistry, Acharya Nagarjuna University, Nagaruna Nagar, Guntur, A.P, India 2Department of Environmental Sciences, Acharya Nagarjuna University, Nagaruna Nagar, Guntur, A.P, India 3SARC (Scientific and Applied Research Centre), Hyderabad, Telangana, India A B S T R A C T The present study the bioactive compound from the bark ... Read More »

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