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Tag Archives: CHCl3

Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl (N-Me) Leucine

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the ... Read More »

SYNTHESIS AND CHARACTERIZATION OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL (N-ME) TYROSINE

About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the ... Read More »

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