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Tag Archives: 4-[2′-(5′-nitro) imidazolyl]benzoyl(N-Me)-aminoacid

Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl(N-Me) Threonine

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the heterocyclic found ... Read More »

Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl (N-Me) Leucine

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the ... Read More »

SYNTHESIS AND CHARACTERIZATION OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL (N-ME) TYROSINE

About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the ... Read More »

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL(N-Me) AMINO ACID DERIVATIVES

About author : Ramesh Dhani Dept. of  Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: A great number of drugs are heterocyclic compounds, mostly are of synthetic origin, few have obtained from natural resources which include alkaloids, xanthines, cardiac glycosides, vitamins and several antibiotics. Heterocyclic derivatives having two nitrogen atoms oriented in, 1-3 position are endowed with wide spectrum of ... Read More »

SYNTHESIS, CHARACTERIZATION AND ANTHELMINTIC ACTIVITY OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL (N-METHYL) AMINO ACID DERIVATIVES

About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail : dhanipharmachem@gmail.com ABSTRACT: Compound containing the imidazole ring are very important in living system, such as vitamin B12 and several pilocarpin alkaloids. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent ... Read More »

Synthesis and Characterization of 4-[2′-(5′-Nitro) imidazolyl] benzoyl (N-Me)Phenyl alanine

About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the field ... Read More »

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