Saturday , 22 June 2024

Review article on mucoadhesive drug delivery system

Rajat Garg*, Ajay raj Yadav, Rahul Kumar Singh
Department of Pharmaceutics, Rajiv Academy for pharmacy, N.H. #2, Mathura Delhi Road, P.O. Chhatikara, Mathura, Uttar Pradesh, India- 281001.

Drug actions can be improved by mucoadhesive drug delivery system. The disadvantages with the oral drug delivery are the extensive first pass metabolism, instability in acidic medium as a result inadequate absorption of the drugs. However parental route may overcome the drawback related with the oral route but these formulations have high cost, supervision is required and least patient compliance. The buccal mucosa is the main target for bioadhesion system because of a smooth and relatively immobile surface and accessibility. Mucoadhesion can be achieved by using mucoadhesive polymers. Various types of the polymers are used in mucoadhesive delivery system. Polymers are used for adhesion of the dosage form for the mucosa.
Keywords: Mucoadhesive. Mucoadhesive drug delivery.

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