Review Article on Antipyretic Activity of Various Plants

Chandana I Shivashimpi¹, Pavitra V¹, Seema M D¹, Amith Kumar B², Nabarun Mukhopadhyay^2
1Students of Bapuji Pharmacy College, Davanagere, Karnataka
²Asst. Professor, Department of Pharmacognosy, Bapuji Pharmacy College, Karnataka

A  B  S  T  R A C T
Plants are well known for their various uses since ancient times. Especially in medical, pharmaceutical, and food industries they play a major role. Various plants are used to reduce the fever. Fever is also known as pyrexia which is elevated body temperature. Pyrexia may occur due to infection, inflammation and any disease state. Here we are reviewing various plants such as Kalmegha, Drumstick, Bahuphali, Sita ashoka, Indian sarsaparilla, Bitter gourd, Noni, Neem, Fever nut, Custard apple which shows the Antipyretic activity. All these plants contain secondary metabolites such as alkaloids, glycosides, flavonoids, tannins, steroids, saponins, carbohydrates, amino acids, terpenoids and protein brewer’s yeast induced pyrexia s. The antipyretic activity of all these drugs was determined by using e-coli induced pyrexia and brewer’s yeast induced pyrexia method. Herbal drugs are now in great demand in the developing world for primary health care not because they are inexpensive but also for better cultural acceptability, better compatibility with the human body and showing less side effects compared with synthetic drugs like paracetamol, ibuprofen, aspirin etc., Majority of synthetic antipyretic drugs shows side effects such as gastric ulcer, hepatic necrosis and renal damage.
Keywords: Kalmegha, Drumstick, Bahuphali, Sitaashoka, Indian sarsaparilla, Bitter gourd, Noni, Neem, Fever nut, Custard apple, Anti-inflammatory