Tuesday , 5 March 2024

Preliminary Phytochemical Investigation, Antiproliferative Activity and Antioxidant Activity of extracts of Fritillaria roylei

Tufeel Amin Mirand Wajaht A. Shah
Department of Chemistry, University of Kashmir, Hazratbal Srinagar, India-190006

Fritillaria roylei is one of the medcinal plants used in traditional medical system for ailment of various diseases. But scientific study of the plant has been less carried out for which the study was conducted for validation of prevailing medical practice. The soxhlet extraction of the plant were conducted in various solvents (hexane, chloroform, ethyl acetate, methanol and water) differing in polarity. The phytochemical screening of extractsrevealed the presence of alkaloids, saponins and tanins. In vitro Cytotoxicity evaluation against five human cancer cell lines A549 (Lung), C6 (Glioma), T47D (Breast), MCF (Breast), and TH-1(Colon) showed that the extracts of Fritillaria roylei exhibited potent cytotoxic activity. The extracts of Fritillaria royleialso showed antioxidant activity.
Keywords: Fritillaria roylei, cytotoxic, antioxidant.

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