Postdoctoral Research Associate in Analysis and Engineering of the Biosynthesis of Antibiotic Natural Products

Postdoctoral Research Associate in Analysis and Engineering of the Biosynthesis of Antibiotic Natural Products

University of Cambridge -Department of Biochemistry
Salary £27,854 – £36,298 pa
Closing date: 23rd May 2013
The successful candidate will join an active research group in the Sanger building, Department of Biochemistry, Cambridge working in collaboration with other research groups at the Universities of Bristol, Manchester and Warwick, together with Syngenta plc, to investigate the genetics, enzymology and biochemistry of the production of bioactive natural products of potential value in crop protection.
The role of the postholder is to help provide leadership in mining the genomes of selected actinomycete bacteria to identify, analyse and exploit novel assembly-line multienzyme systems that synthesise polyketides, polypeptides and other bioactive natural products of potential future value in plant protection.
The successful candidate should have a background in organic chemistry or biochemistry, with extensive research experience in molecular microbiology and molecular biology and a PhD in a relevant science In particular, it is essential that the postholder have significant previous experience and a strong publication track record in working with Streptomyces and allied antibiotic-producing filamentous bacteria, including fermentation, the isolation and analysis of natural products, and the initial determination of their structure by hplc-linked mass spectrometry.
This post carries significant responsibility for driving forward an ambitious programme of enzyme and pathway engineering, and the successful candidate will be expected to show initiative and creativity in experimental design. He/she must be a good communicator and able and willing to work closely with other research scientists within the consortium.
For full details of this post please visit the University of Cambridge
webpage via the link below:http://www.jobs.cam.ac.uk/job/1389/
The post is available from 1 June 2013, Fixed-term: The funds for this post are available for 3 years in the first instance with the possibility of renewal for a further period.
To apply, please complete a CHRIS/6 application form (Parts I and III only), downloadable from the Apply button below and return it, along with a CV, to [email protected].
Please quote reference PH01161 on your application and in any correspondence about this vacancy.
The University values diversity and is committed to equality of opportunity.
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