Sunday , 3 March 2024

Pharmacological evolution of Co(II), Ni(II),Cu(II) and Zn(II) metal complexes of 2-Hydroxy-5- methyl acetophenone-N, N’-ethylenediimine Schiff base

Sandip R. Kelode
Department of Engg. Chemistry,
Jagadambha College of Engineering and Technology, Yavatmal, India

The synthesized metal complexes Co(II), Ni(II), Cu(II) and Zn(II) of Schiff base have been condensing by 2-hydroxy-5-methyl acetophenone with ethylene diamine. The metal complexes were obtained as a result of interaction of Schiff base ligand. Schiff base have been synthesized and characterized on the basis of elemental analysis, Infrared and 1H NMR, analysis. The Schiff base commonly coordinates through the oxygen atom of phenolic OH group and the nitrogen atom of azomethine group, which is confirmed by IR spectral data. Further conclusive evidence of the coordination of the Schiff bases with the metal ions was shown by the appearance of new bands due to v(M-N) and v(M-O) in the metal complexes. The metal complexes have been examined against the growth of bacteria to assess their Pharmacological evolution.
Key words: Schiff base, Spectral, Antimicrobial studies

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